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KMID : 0390219990100010066
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Journal of Clinical Otolaryngology, Head and Neck Surgery
1999 Volume.10 No. 1 p.66 ~ p.70
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A Clinical Study of Squamous Cell Carcinoma Arising in Inverted Papilloma
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박성국/Seong Kook Park
조홍욱/박춘근/Hong Wook Cho/Choon Keun Park
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Abstract
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Background and Objectives : Inverted Papilloma is a benign neoplastic lesion which
shows high recurrence rate and possibility of with malignacy. Squamous cell carcinoma
arising in inverted papilloma has been reported in the literature. But most reported
series have very few patients with this disease. This report was conducted to investigate
clinical characteristics and treatment outcome of squamous cell carcinoma
arising in inverted papilloma. Materials and Methods : We reviewed clinical data of eight
patients who have been treated from January 1982 to March 1998 for squamous cell
carcinoma arising in inverted papilloma. Results : Synchronus tumor was 6 cases and
metachronus tumor was 2 cases. The most common presenting symptom was unilateral
nasal obstruction. Others were nasal bleeding, rhinorrhea, and periorbital swelling with
eyeball deviation. Stage at diagnosis was according to modified Kadish staging system,
5 cases of B stage, I of C stage and 2 of D stage. All patients were treated with
surgical excision and postoperative radiation therapy was done in 6 cases. In 2 B, all
lived more than 3 years and prognosis was better than C stage. Conclusion : We suggest
that modified Kadish staging system is more helpful than maxillary carcinoma staging
system in prediction of prognosis of squamous cell carcinoma arising in inverted
papilloma. We recommend wide surgical excision in squamous cell carcinoma and long
term follow up period after inverted papilloma operation due to the possibility of
metachronus.
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